The 2018/2019 LaLiga season kicks off on the weekend of August 18, with Clasico games between Real Madrid and Barcelona in October and March, the Royal Spanish Football Federation (RFEF) announced on Tuesday.
The first Clasico of the LaLiga season falls on the weekend October 28 at the Camp Nou.
The return fixture will be on March 3, 2019 at the Santiago Bernabeu.
The last league games will be played on the weekend of May 19, 2019.
LaLiga champions and Copa del Rey winners Barcelona take on beaten cup finalists Sevilla on August 12 in Tangier, Morocco, in the Spanish Supercup, the traditional curtain-raiser of the season.
The RFEF has also approved an asymmetrical fixture list ahead of the new campaign, as used in the Premier League rather than the traditional calendar format.